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Primary open-angle glaucoma ( POAG ) is a blinding disease. Two important risk factors for this disease are a positive family history and elevated intraocular pressure ( IOP ), which is also highly he ...


Secukinumab, a fully human anti-interleukin-17A monoclonal antibody, exhibited promising activity in a proof-of-concept study when administered in intravenous ( IV ) doses to patients with active, chr ...


The purpose of a study was to evaluate the effect of monthly intravitreal Ranibizumab ( Lucentis ) on hard exudate ( HE ) area and the impact of hard exudate on visual acuity ( VA ) outcomes in diabet ...


A single-practice retrospective chart review has reported on long-term visual outcomes in patients receiving continuous fixed-interval dosing of anti-vascular endothelial growth factor ( VEGF ) treatm ...


Eylea ( Aflibercept ) injection has been recommended for approval by the European Committee for Medicinal Products for Human Use ( CHMP ) for the treatment of visual impairment due to macular edema s ...


The FDA ( Food and Drug Administration ) has accepted for priority review the supplemental biologics license application ( sBLA ) for Eylea ( Aflibercept ) injection for the treatment of diabetic reti ...


The clinical and demographic profile of uveitis-related ocular hypertension ( OHT ) was studied and risk factors predisposing to development of ocular hypertension in uveitis were evaluated. Two ...


The aim of a study was to assess the clinical response to Golimumab ( Simponi ) in patients with non-infectious uveitis from a single centre that had previously been treated with other anti-TNF-alpha ...


In September 2014, the FDA ( Food and Drug Administration ) granted Eylea ( Aflibercept ) injection Breakthrough Therapy designation for the treatment of diabetic retinopathy in patients with diabetic ...


A study has assessed the safety and efficacy of Tocilizumab ( Actemra; RoActemra ) in patients with severe and refractory non-infectious uveitis. Eight consecutive unselected patients with severe a ...


Long-term daily multivitamin supplement use may lower cataract risk in men, according to a study of nearly 15,000 male physicians published in Ophthalmology, the journal of the American Academy of Oph ...


A new study published in the Journal of the American Association for Pediatric Ophthalmology and Strabismus ( AAPOS ) suggests that the biologic agent Adalimumab ( Humira ) may be a viable treatment o ...


The aim of the GEFAL trial was to evaluate the relative efficacy and safety profile of Bevacizumab ( Avastin ) versus Ranibizumab ( Lucentis ) intravitreal injections for the treatment of neovascular ...


Bayer HealthCare has announced that Eylea ( Aflibercept solution for injection ) has been approved by the European Commission ( EC ) for the treatment of visual impairment due to macular edema seconda ...


The aim of a study was to assess the efficacy of Adalimumab ( Humira ) in patients with active non-infectious uveitis in three different centres. In a retrospective study researchers have identifie ...


The EMA’s Committee for Medicinal Products for Human Use ( CHMP ) has recommended marketing authorisation for Jetrea, a medicinal product indicated for the treatment of adults with vitreomacular tract ...


Results for VEGF Trap-Eye ( Aflibercept ophthalmic solution ) from the Phase 3 MYRROR study in myopic choroidal neovascularization ( mCNV ) were presented. Patients receiving VEGF Trap-Eye at a dose o ...


Tumour necrosis factor ( TNF ) blockers have been demonstrated to be effective in the treatment of systemic and ocular inflammatory diseases. Researchers have conducted a prospective, multicentre, o ...


The experimental drug Selumetinib is the first targeted therapy to demonstrate significant clinical benefit for patients with metastatic uveal melanoma.The findings are potentially practice-changing f ...


Nonetheless biologic modifier therapies are available treatment strategies for sight-threatening uveitis in children, the lack of evidence from head-to-head randomized controlled studies limits our un ...


Regeneron has announced that detailed one-year results from the VIEW 1 and VIEW 2 phase 3 studies of Aflibercept ( Eylea ) injection, published in the journal Ophthalmology. Eylea, for the treatmen ...


Corticosteroids are the mainstay of treatment for immune-mediated diseases, including non-infectious uveitis and ocular inflammation, because they are inexpensive, potent and rapidly effective. Howeve ...


Taking oral antiviral medications following infection with the herpes simplex virus may be associated with a reduced risk of recurring eye-related manifestations of the disease.Herpes simplex virus ( ...


All three commonly used TNF blockers ( Infliximab, Etanercept and Adalimumab ) were initially approved for the treatment of rheumatoid arthritis, and were subsequently approved for a number of other s ...


People whose diet includes a lot of red meat are more likely to develop the early stages of an eye condition known as age-related macular degeneration ( AMD ), which is the leading cause of vision los ...


A small group of patients with severe Graves' eye disease experienced rapid improvement of their symptoms — and improved vision — following treatment with the drug Rituximab MabThera, Rituxan ). Infla ...


Researchers from Boston University School of Medicine ( BUSM ) and the VA Boston Healthcare System have shown, at 6 months in a small group of patients, that there is no difference in efficacy between ...


Patients with diabetes who take the medication Rosiglitazone ( Avandia ) may be less likely to develop the eye disease proliferative diabetic retinopathy or to experience reductions in visual acuity.P ...


A low-vision therapy program that includes a home visit, counseling, assistive devices such as magnifiers and assignments to practice using them appears to significantly improve vision in veterans wit ...


Corneal grafts obtained from donors dying in the hospital or with cancer may be associated with an increased risk of infection for the recipient. Infection is an uncommon but serious complication o ...


Research conducted by Reza Dana, at the Massachusetts Eye and Ear Infirmary ( MEEI ) Cornea Service, and colleagues at the Schepens Eye Research Institute, have found for the first time that topical d ...


Individuals who have higher dietary intake of foods with omega-3 fatty acids and higher fish consumption have a reduced risk of advanced age-related macular degeneration, while those with higher serum ...


Current and past smokers appear to have a higher risk of developing late age-related macular degeneration than those who have never smoked. Age-related macular degeneration ( AMD ) is the leading c ...


The interplay between genetic predisposition and exposure to modifiable risk factors can multiply the risk for age-related macular degeneration. Age-related macular degeneration ( AMD ) can cause b ...


The statins are associated with a lower incidence of nuclear cataract, the most common type of age-related cataract. Statins are widely used to decrease serum cholesterol for cardiovascular disease ...


A study, led by researchers at Columbia University Medical Center and published in Nature Genetics, pinpoints the role that two genes, Factor H and Factor B, play in the development of nearly three ou ...


A paper published in Trends in Neuroscience by Nicolas G. Bazan, at Louisiana State University ( LSU ) Health Sciences Center in New Orleans, reports on the role that the omega-3 fatty acids in fish o ...


Early studies indicate cannabidiol works to protect the eye from growing a plethora of leaky blood vessels, the hallmark of diabetic retinopathy, says Gregory I. Liou, at the Medical College of Georgi ...


Age-related macular degeneration ( AMD ), one of the leading causes of vision loss in older adults and a person's risk may partly depend upon diet, could be due to quality of carbohydrates, rather tha ...


Fusarium is associated with an increasing number of cases of keratitis. Infections caused by fungi can be devastating to both the structure of the eye and the patient's vision. Keratitis, or swellin ...


A small study found that major intestinal surgery, including stomach reduction for obesity, may boost the chances of subsequent vitamin A deficiency. The researchers have based their findings on th ...


Some patients with glaucoma appear to have higher pressure in their eyes during sleep at night than during the day when it is usually measured, possibly putting them at higher risk for progression of ...


People who have elevated homocysteine in their blood, an amino acid that is a known biomarker for cardiovascular disease, may also be at an increased risk of developing age-related macular degeneratio ...


Researchers at the Massachusetts Eye and Ear Infirmary ( MEEI ) have found that Chlamydia pneumoniae, a bacterium linked to heart disease and capable of causing chronic inflammation, was present in th ...


Passive smoking almost doubles the risk of the progressively degenerative eye disease, age related macular degeneration, shows research, published in the British Journal of Ophthalmology. The macu ...


Researchers at Washington University School of Medicine in St. Louis have found that cells making up a non-visual system in the eye are in place and functioning long before the rods and cones that pro ...


A study, published in the JAMA, has found that a diet with a high intake of beta carotene, vitamins C and E, and zinc is associated with a substantially reduced risk of age-related macular degeneratio ...


Researchers led by the Johns Hopkins Wilmer Eye Institute have determined that the corneal infection rate associated with the use of 30-day -extended-wear contact lenses made from silicone hydrogel is ...


In a large prospective study of physicians followed over 14 years, Schaumberg et al. found that greater adult height and a pattern of abdominal adiposity were each independent risk factors for catarac ...


Age-related macular degeneration ( AMD ) is the leading cause of blindness in older patients in the developed world. Vascular endothelial growth factor is one of the key mediators stimulating the ...



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